NAD NON-IV Therapy

Our New Nebulization “NAD NON-IV” Therapy © NAD Wellness Centers 2020

The simplest and most natural route of drug delivery to the lungs is the inhaled one. From the historical and medical point of view, it was a Greek, Pedanus Discorides,
the father of the science of pharmacy, who, during the first century (100 AD) prescribed inhaled fumigation.

In the middle of the nineteenth century (1800’s), the onslaught of tuberculosis brought back into practice the efficacious use of antiseptic aerosol therapy (nebulization). With the discovery of adrenaline, ephedrine aerosol nebulization enjoyed a
rebirth.

Nebulizers are the oldest form of aerosol generation and can be used at any age, for any disease severity (Geller, 2005). Even
though nebulizers have been commonly used for many years, their basic design and performance has changed little over the past
25 years (Hess, 2000).

It has been noted that the key aim of nebulized therapy is to deliver a therapeutic substance to the lungs in an effective and short time frame. Nicotinamide Adenine Dinucleotide (NAD) is an all-natural substance and the number one coenzyme that can now
for the first time easily be nebulized in a short period of time with little to no side effects.

In 1949 in the United States, with the improvement of nebulizer systems and new nebulized medications, compression and
ultrasonic nebulizers made their first appearance in the form of humidifiers, but doctors were quick to add medications to
produce therapeutic aerosols.

Medications, including natural ones such as NAD, are increasingly being nebulized, however, the only currently effective
transporter for NAD by nebulization is a solution called Isobiscum.

Note…The normal protocol for using NAD therapy is through an IV drip. This can take up to six hours per day, with the first day being 9 hours. Therefore, it is difficult to administer NAD to young children and those that have an inversion to needles. On the contrary, nebulizing NAD only takes 2.5 hours. The patient merely sits in a chair with an oxygen mask to inhale NAD through a nebulizer. Children of all ages have heretofore had no difficulty with NAD therapy.

Dr. James Chappell is part of the NAD Wellness Team. Dr. Jim and is a medical herbalist, clinical nutritionist, traditional naturopath, formulation chemist, and chiropractic physician. Our teams Isobiscum is the only known effective transporter of nutraceutical and botanical concentrates. Since 1971, Dr. Chappell has specialized in chronic, severe, and so-called terminal illness.

The NAD Wellness Centers in the USA and its affiliates Internationally are the ONLY facilities licensed in the world to use
Isobiscum to nebulize NAD.

Our Proprietary NAD NON-IV Nebulization Treatment

History of aerosol therapy: liquid nebulization to MDIs to DPIs.

Inhaled therapies have been used since ancient times and may have had their origins with the smoking of datura preparations in
India 4,000 years ago. In the late 18th and in the 19th century, earthenware inhalers were popular for the inhalation of air drawn through infusions of plants and other ingredients. Atomizers and nebulizers were developed in the mid-1800s in France and were thought to be an outgrowth of the perfume industry as well as a response to the fashion of inhaling thermal waters at spas.

Around the turn of the 20th century, combustible powders and cigarettes containing stramonium were popular for asthma and other lung complaints. Following the discovery of the utility of epinephrine for treating asthma, hand-bulb nebulizers were developed, as well as early compressor nebulizers.

There have been remarkable advances in the technology of devices and formulations for inhaled drugs in the past 50 years. These have been influenced greatly by scientific developments in several areas: theoretical modeling and indirect measures of lung deposition, particle sizing techniques and in vitro deposition studies, scintigraphy deposition studies, pharmacokinetics, and pharmacodynamics, and the 1987 Montreal Protocol, which banned chlorofluorocarbon propellants.

We are now in an era of a New Paradigm Rapid Technologic progress in inhaled drug delivery and applications of Advanced
Nebulization Science. This is being done with the use of the aerosolized route for drugs for systemic therapy and for gene replacement therapy, use of aerosolized antimicrobials and immunosuppressants, and interest in specific targeting of inhaled drugs.